FoxC1/2 Rabbit Polyclonal Antibody

Name: FoxC1/2 Rabbit Polyclonal Antibody
Brand: ELK Biotechnology
SKU: ES5279
Price: 248.0 USD
Availability: InStock

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FoxC1/2 Rabbit Polyclonal Antibody

Overview

Product name:	FoxC1/2 rabbit pAb
Alternative Names:	FOXC1; FKHL7; FREAC3; Forkhead box protein C1; Forkhead-related protein FKHL7; Forkhead-related transcription factor 3; FREAC-3; FOXC2; FKHL14; MFH1; Forkhead box protein C2; Forkhead-related protein FKHL14; Mesenchyme fork head protein 1;
Applications:	WB;IHC;IF;ELISA
Recommended Dilutions:	Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.
Immunogen:	The antiserum was produced against synthesized peptide derived from human FOXC1/2. AA range:151-200
Storage:	Rabbit
Storage:	-20°C/1 year
Clonality:	Polyclonal
Isotype:	IgG
Concentration:	1 mg/ml
Observed Band:	57kD
GeneID（Human）:	2296/2303
Human Swiss-Prot No:	Q12948/Q99958
Cellular localization:	Nucleus . Colocalizes with PITX2 isoform 3 in the nucleus at subnuclear chromatine regions (PubMed:16449236). Colocalizes with CBX5 to a heterochromatin-rich region of the nucleus (PubMed:15684392). Colocalizes with GLI2 in the nucleus (By similarity). .
Background:	This gene belongs to the forkhead family of transcription factors which is characterized by a distinct DNA-binding forkhead domain. The specific function of this gene has not yet been determined; however, it has been shown to play a role in the regulation of embryonic and ocular development. Mutations in this gene cause various glaucoma phenotypes including primary congenital glaucoma, autosomal dominant iridogoniodysgenesis anomaly, and Axenfeld-Rieger anomaly. [provided by RefSeq, Jul 2008],
Species Reactivity:	Human;Mouse;Rat

Western Blot analysis of hela cells using FoxC1/2 Polyclonal Antibody diluted at 1:2000 cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA).
Western blot analysis of lysates from RAW264.7 cells, using FOXC1/2 Antibody. The lane on the right is blocked with the synthesized peptide.
Western blot analysis of the lysates from Jurkat cells using FOXC1/2 antibody.
Immunohistochemical analysis of paraffin-embedded human tonsil. 1, Tris-EDTA,pH9.0 was used for antigen retrieval. 2 Antibody was diluted at 1:200(4° overnight.3,Secondary antibody was diluted at 1:200(room temperature, 45min).

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FoxC1/2 Rabbit Polyclonal Antibody

FoxC1/2 Rabbit Polyclonal Antibody

Overview