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ELK Biotechnology

ES5259

Rab11-FIP2 Rabbit Polyclonal Antibody

Rab11-FIP2 Rabbit Polyclonal Antibody

$248.00 USD
$248.00 USD
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Rab11-FIP2 Rabbit Polyclonal Antibody

Overview

Product name: Rab11-FIP2 rabbit pAb
Alternative Names: RAB11FIP2; KIAA0941; Rab11 family-interacting protein 2; Rab11-FIP2; NRip11
Applications: WB;ELISA;IHC
Recommended Dilutions: WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
Immunogen: The antiserum was produced against synthesized peptide derived from human RAB11FIP2. AA range:340-389
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 58kD
GeneID（Human）: 22841
Human Swiss-Prot No: Q7L804
Cellular localization: Cell projection, phagocytic cup . Cell membrane; Peripheral membrane protein. Recycling endosome membrane; Peripheral membrane protein. Translocates with RAB11A from the vesicles of the endocytic recycling compartment (ERC) to the plasma membrane.
Background: function:A Rab11 effector protein acting in the regulation of the transport of vesicles from the endosomal recycling compartment (ERC) to the plasma membrane. Also involved in receptor-mediated endocytosis and membrane trafficking of recycling endosomes, probably originating from clathrin-coated vesicles. Binds preferentially to phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3) and phosphatidic acid (PA).,similarity:Contains 1 C2 domain.,subcellular location:Translocates with RAB11A from the vesicles of the endocytic recycling compartment (ERC) to the plasma membrane.,subunit:Homooligomerizes in a Rab11-independent manner. Forms an heterooligomeric complex with RAB11FIP4. Interacts with AP2A1, MYO5B, RAB11A, RAB11B, RAB25 and REPS1. Interacts with RAB11A/RAB11B that has been activated by GTP binding.,
Species Reactivity: Human;Mouse
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