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ELK Biotechnology

ES5253

Fhit (phospho Tyr114) Rabbit Polyclonal Antibody

Fhit (phospho Tyr114) Rabbit Polyclonal Antibody

$248.00 USD
$248.00 USD
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Fhit (phospho Tyr114) Rabbit Polyclonal Antibody

Overview

Product name: Fhit (phospho Tyr114) rabbit pAb
Alternative Names: FHIT; Bis(5'-adenosyl)-triphosphatase; AP3A hydrolase; AP3Aase; Diadenosine 5'; 5'''-P1,P3-triphosphate hydrolase; Dinucleosidetriphosphatase; Fragile histidine triad protein
Applications: IHC;IF;ELISA
Recommended Dilutions: Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human FHIT around the phosphorylation site of Tyr114. AA range:80-129
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
GeneID（Human）: 2272
Human Swiss-Prot No: P49789
Cellular localization: Cytoplasm . Mitochondrion . Nucleus .
Background: This gene, a member of the histidine triad gene family, encodes a diadenosine 5',5'''-P1,P3-triphosphate hydrolase involved in purine metabolism. The gene encompasses the common fragile site FRA3B on chromosome 3, where carcinogen-induced damage can lead to translocations and aberrant transcripts of this gene. In fact, aberrant transcripts from this gene have been found in about half of all esophageal, stomach, and colon carcinomas. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2009],
Species Reactivity: Human;Rat;Mouse;
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