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ELK Biotechnology
SKU:ES5239
Fibrinogen β Rabbit Polyclonal Antibody
Fibrinogen β Rabbit Polyclonal Antibody
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Fibrinogen β Rabbit Polyclonal Antibody
Overview
| Product name: | Fibrinogen β rabbit pAb |
| Alternative Names: | FGB; Fibrinogen beta chain |
| Applications: | WB;ELISA |
| Recommended Dilutions: | Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications. |
| Immunogen: | Synthesized peptide derived from the Internal region of human Fibrinogen β. |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 55kD |
| GeneID（Human）: | 2244 |
| Human Swiss-Prot No: | P02675 |
| Cellular localization: | Secreted . |
| Background: | The protein encoded by this gene is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia and thrombotic tendency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2014], |
| Species Reactivity: | Human;Rat;Mouse; |
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