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ELK Biotechnology
SKU:ES5075
eIF4B Rabbit Polyclonal Antibody
eIF4B Rabbit Polyclonal Antibody
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$248.00 USD
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eIF4B Rabbit Polyclonal Antibody
Overview
| Product name: | eIF4B rabbit pAb |
| Alternative Names: | EIF4B; Eukaryotic translation initiation factor 4B; eIF-4B |
| Applications: | WB;IHC;IF;ELISA |
| Recommended Dilutions: | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human eIF4B. AA range:388-437 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 70kD |
| GeneID(Human): | 1975 |
| Human Swiss-Prot No: | P23588 |
| Cellular localization: | cytosol,polysome,eukaryotic translation initiation factor 4F complex,dendrite,neuronal cell body, |
| Background: | function:Required for the binding of mRNA to ribosomes. Functions in close association with EIF4-F and EIF4-A. Binds near the 5'-terminal cap of mRNA in presence of EIF-4F and ATP. Promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both EIF4-A and EIF4-F.,similarity:Contains 1 RRM (RNA recognition motif) domain.,subunit:Self-associates and interacts with EIF3 p170 subunit., |
| Species Reactivity: | Human;Mouse |
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Immunofluorescence analysis of A549 cells, using eIF4B Antibody. The picture on the right is blocked with the synthesized peptide. -
Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue, using eIF4B Antibody. The picture on the right is blocked with the synthesized peptide. -
Western blot analysis of lysates from HepG2 and HUVEC cells, using eIF4B Antibody. The lane on the right is blocked with the synthesized peptide.
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