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ELK Biotechnology
SKU:ES4963
Nesprin-3 Rabbit Polyclonal Antibody
Nesprin-3 Rabbit Polyclonal Antibody
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Nesprin-3 Rabbit Polyclonal Antibody
Overview
| Product name: | Nesprin-3 rabbit pAb |
| Alternative Names: | SYNE3; C14orf49; Nesprin-3; Nuclear envelope spectrin repeat protein 3 |
| Applications: | WB;IF;ELISA |
| Recommended Dilutions: | Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human C14orf49. AA range:169-218 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 115kD |
| GeneID(Human): | 161176 |
| Human Swiss-Prot No: | Q6ZMZ3 |
| Cellular localization: | Nucleus outer membrane ; Single-pass type IV membrane protein . Nucleus envelope . Rough endoplasmic reticulum . |
| Background: | function:Involved in the maintenance of nuclear organization and structural integrity. Probable anchoring protein which theters the nucleus to the cytoskeleton by binding PLEC1/Plectin which can associate with the intermediate filament system.,similarity:Belongs to the nesprin family.,similarity:Contains 1 KASH domain.,similarity:Contains 2 spectrin repeats.,subcellular location:Located at the rough reticulum endoplasmic (RER) in some cells.,subunit:Interacts with actin-binding domain of PLEC1/plectin., |
| Species Reactivity: | Human;Mouse |
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Western Blot analysis of Jurkat cells using Nesprin-3 Polyclonal Antibody cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA). -
Western blot analysis of lysates from Jurkat cells, using C14orf49 Antibody. The lane on the right is blocked with the synthesized peptide.
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