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ELK Biotechnology

SKU:ES4963

Nesprin-3 Rabbit Polyclonal Antibody

Nesprin-3 Rabbit Polyclonal Antibody

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Nesprin-3 Rabbit Polyclonal Antibody

Overview

Product name: Nesprin-3 rabbit pAb
Alternative Names: SYNE3; C14orf49; Nesprin-3; Nuclear envelope spectrin repeat protein 3
Applications: WB;IF;ELISA
Recommended Dilutions: Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human C14orf49. AA range:169-218
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 115kD
GeneID(Human): 161176
Human Swiss-Prot No: Q6ZMZ3
Cellular localization: Nucleus outer membrane ; Single-pass type IV membrane protein . Nucleus envelope . Rough endoplasmic reticulum .
Background: function:Involved in the maintenance of nuclear organization and structural integrity. Probable anchoring protein which theters the nucleus to the cytoskeleton by binding PLEC1/Plectin which can associate with the intermediate filament system.,similarity:Belongs to the nesprin family.,similarity:Contains 1 KASH domain.,similarity:Contains 2 spectrin repeats.,subcellular location:Located at the rough reticulum endoplasmic (RER) in some cells.,subunit:Interacts with actin-binding domain of PLEC1/plectin.,
Species Reactivity: Human;Mouse
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