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ELK Biotechnology

ES4906

TGR5 Rabbit Polyclonal Antibody

TGR5 Rabbit Polyclonal Antibody

$248.00 USD
$248.00 USD
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TGR5 Rabbit Polyclonal Antibody

Overview

Product name: TGR5 rabbit pAb
Alternative Names: GPBAR1; TGR5; G-protein coupled bile acid receptor 1; G-protein coupled receptor GPCR19; hGPCR19; Membrane-type receptor for bile acids; M-BAR; hBG37; BG37
Applications: WB;ELISA;IHC
Recommended Dilutions: WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
Immunogen: The antiserum was produced against synthesized peptide derived from human GPBAR. AA range:11-60
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
GeneID（Human）: 151306
Human Swiss-Prot No: Q8TDU6
Cellular localization: Cell membrane ; Multi-pass membrane protein .
Background: This gene encodes a member of the G protein-coupled receptor (GPCR) superfamily. This enzyme functions as a cell surface receptor for bile acids. Treatment of cells expressing this GPCR with bile acids induces the production of intracellular cAMP, activation of a MAP kinase signaling pathway, and internalization of the receptor. The receptor is implicated in the suppression of macrophage functions and regulation of energy homeostasis by bile acids. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008],
Species Reactivity: Human;Rat;Mouse;
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