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ELK Biotechnology
SKU:ES4829
Polyclonal AntibodyP5 Rabbit Polyclonal Antibody
Polyclonal AntibodyP5 Rabbit Polyclonal Antibody
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Polyclonal AntibodyP5 Rabbit Polyclonal Antibody
Overview
| Product name: | PABP5 rabbit pAb |
| Alternative Names: | PABPC5; PABP5; Polyadenylate-binding protein 5; PABP-5; Poly(A)-binding protein 5 |
| Applications: | WB;IHC;IF;ELISA |
| Recommended Dilutions: | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human PABPC5. AA range:184-233 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 43kD |
| GeneID(Human): | 140886 |
| Human Swiss-Prot No: | Q96DU9 |
| Cellular localization: | Cytoplasm .; [Isoform 2]: Mitochondrion matrix . Co-fractionates with mtDNA and co-immunoprecipitates with the mitochondrial poly(A) polymerase. |
| Background: | This gene encodes a protein that binds to the polyA tail found at the 3' end of most eukaryotic mRNAs. It is thought to play a role in the regulation of mRNA metabolic processes in the cytoplasm. This gene is located in a gene-poor region within the X-specific 13d-sY43 subinterval of the chromosome Xq21.3/Yp11.2 homology block. It is located close to translocation breakpoints associated with premature ovarian failure, and is therefore a potential candidate gene for this disorder. [provided by RefSeq, May 2010], |
| Species Reactivity: | Human;Rat;Mouse; |
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Western blot analysis of lysates from K562 cells, using PABPC5 Antibody. The lane on the right is blocked with the synthesized peptide. -
Western blot analysis of the lysates from HeLa cells using PABPC5 antibody. -
Immunohistochemical analysis of paraffin-embedded human Squamous cell carcinoma of lung. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
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