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ELK Biotechnology
SKU:ES4765
Acetyl Histone H1 (K25) Rabbit Polyclonal Antibody
Acetyl Histone H1 (K25) Rabbit Polyclonal Antibody
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Acetyl Histone H1 (K25) Rabbit Polyclonal Antibody
Overview
| Product name: | Acetyl Histone H1 (K25) rabbit pAb |
| Alternative Names: | H1FOO; H1OO; OSH1; Histone H1oo; Oocyte-specific histone H1; Oocyte-specific linker histone H1; osH1;H1K25AC |
| Applications: | WB;IHC;IF;ELISA |
| Recommended Dilutions: | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human Histone H1 around the acetylated site of Lys25. AA range:131-180 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 20kD |
| GeneID(Human): | 132243 |
| Human Swiss-Prot No: | Q8IZA3 |
| Cellular localization: | Cytoplasm . Nucleus . Chromosome . |
| Background: | Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. The protein encoded is a replication-independent histone that is a member of the histone H1 family. This gene contains introns, unlike most histone genes. The related mouse gene is expressed only in oocytes. [provided by RefSeq, Oct 2015], |
| Species Reactivity: | Human;Monkey |
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Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using Histone H1 (Acetyl-Lys25) Antibody. The picture on the right is blocked with the synthesized peptide. -
Western blot analysis of lysates from COS7 cells, treated with TSA 400nM 24h, using Histone H1 (Acetyl-Lys25) Antibody. The lane on the right is blocked with the synthesized peptide.
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