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ELK Biotechnology
SKU:ES4722
Repetin Rabbit Polyclonal Antibody
Repetin Rabbit Polyclonal Antibody
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$248.00 USD
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Repetin Rabbit Polyclonal Antibody
Overview
| Product name: | Repetin rabbit pAb |
| Alternative Names: | RPTN; Repetin |
| Applications: | WB;IHC |
| Recommended Dilutions: | WB 1:500-2000;IHC-p 1:50-300 |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human RPTN. AA range:648-697 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 90kD |
| GeneID(Human): | 126638 |
| Human Swiss-Prot No: | Q6XPR3 |
| Cellular localization: | Secreted, extracellular space, extracellular matrix. |
| Background: | domain:Can be divided into a N-terminal domain with significant homology to S100-like calcium-binding proteins, a central domain containing a series of short tandem repeats, and two flanking segments with low homology to the consensus sequences of the central repeats.,function:Involved in the cornified cell envelope formation. Multifunctional epidermal matrix protein. Reversibly binds calcium.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,PTM:Potential substrate of transglutaminase. Some arginines are probably converted to citrullines by peptidylarginine deimidase.,similarity:Belongs to the S100-fused protein family.,similarity:Contains 2 EF-hand domains.,tissue specificity:Expression is scattered in the normal epidermis but strong in the acrosyringium, the inner hair root sheat and in the filiform papilli of the tongue., |
| Species Reactivity: | Human;Rat;Mouse; |
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Western Blot analysis of HeLa cells using Repetin Polyclonal Antibody -
Western blot analysis of RPTN Antibody. The lane on the right is blocked with the RPTN peptide. -
Western blot analysis of the lysates from HepG2 cells using RPTN antibody. -
Immunohistochemical analysis of paraffin-embedded human Breast cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
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