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ELK Biotechnology
SKU:ES4681
CYP2R1 Rabbit Polyclonal Antibody
CYP2R1 Rabbit Polyclonal Antibody
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$248.00 USD
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CYP2R1 Rabbit Polyclonal Antibody
Overview
| Product name: | CYP2R1 rabbit pAb |
| Alternative Names: | CYP2R1; Vitamin D 25-hydroxylase; Cytochrome P450 2R1 |
| Applications: | WB;IHC;IF;ELISA |
| Recommended Dilutions: | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human CYP2R1. AA range:251-300 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 52kD |
| GeneID(Human): | 120227 |
| Human Swiss-Prot No: | Q6VVX0 |
| Cellular localization: | Endoplasmic reticulum membrane ; Peripheral membrane protein. Microsome membrane ; Peripheral membrane protein. |
| Background: | This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme is a microsomal vitamin D hydroxylase that converts vitamin D into the active ligand for the vitamin D receptor. A mutation in this gene has been associated with selective 25-hydroxyvitamin D deficiency. [provided by RefSeq, Jul 2008], |
| Species Reactivity: | Human;Mouse;Monkey |
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Western Blot analysis of HT-29 cells using CYP2R1 Polyclonal Antibody -
Immunohistochemistry analysis of paraffin-embedded human colon carcinoma, using Cytochrome P450 2R1 Antibody. The picture on the right is blocked with the synthesized peptide. -
Western blot analysis of lysates from HT29 cells, using Cytochrome P450 2R1 Antibody. The lane on the right is blocked with the synthesized peptide. -
Western blot analysis of the lysates from HT-29 cells using Cytochrome P450 2R1 antibody.
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