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ELK Biotechnology
SKU:ES4636
mAChR M5 Rabbit Polyclonal Antibody
mAChR M5 Rabbit Polyclonal Antibody
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$248.00 USD
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mAChR M5 Rabbit Polyclonal Antibody
Overview
| Product name: | mAChR M5 rabbit pAb |
| Alternative Names: | CHRM5; Muscarinic acetylcholine receptor M5 |
| Applications: | WB;IF;ELISA |
| Recommended Dilutions: | Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human CHRM5. AA range:281-330 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 60kD |
| GeneID(Human): | 1133 |
| Human Swiss-Prot No: | P08912 |
| Cellular localization: | Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. |
| Background: | The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The clinical implications of this receptor are unknown; however, stimulation of this receptor is known to increase cyclic AMP levels. [provided by RefSeq, Jul 2008], |
| Species Reactivity: | Human;Rat;Mouse; |
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Western Blot analysis of Jurkat cells using mAChR M5 Polyclonal Antibody -
Immunofluorescence analysis of A549 cells, using CHRM5 Antibody. The picture on the right is blocked with the synthesized peptide. -
Western blot analysis of lysates from LOVO and RAW264.7 cells, using CHRM5 Antibody. The lane on the right is blocked with the synthesized peptide. -
Western blot analysis of the lysates from K562 cells using CHRM5 antibody.
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