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ELK Biotechnology
SKU:ES4628
Ataxin-2L Rabbit Polyclonal Antibody
Ataxin-2L Rabbit Polyclonal Antibody
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Ataxin-2L Rabbit Polyclonal Antibody
Overview
| Product name: | Ataxin-2L rabbit pAb |
| Alternative Names: | ATXN2L; A2D; A2LG; A2LP; A2RP; Ataxin-2-like protein; Ataxin-2 domain protein; Ataxin-2-related protein |
| Applications: | WB;ELISA |
| Recommended Dilutions: | Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human ATXN2L. AA range:571-620 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 113kD |
| GeneID(Human): | 11273 |
| Human Swiss-Prot No: | Q8WWM7 |
| Cellular localization: | Membrane ; Peripheral membrane protein . Cytoplasm . Nucleus speckle . Cytoplasmic granule . Predominantly cytoplasmic but is also detected in nuclear speckles (PubMed:23209657). Component of cytoplasmic stress granules (PubMed:23209657). Inhibition of methylation alters nuclear localization (PubMed:25748791). Methylation does not seem to be required for localization to stress granules under stress conditions (PubMed:25748791). . |
| Background: | This gene encodes an ataxin type 2 related protein of unknown function. This protein is a member of the spinocerebellar ataxia (SCAs) family, which is associated with a complex group of neurodegenerative disorders. Several alternatively spliced transcripts encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008], |
| Species Reactivity: | Human;Rat;Mouse; |
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Western Blot analysis of 293T cells using Ataxin-2L Polyclonal Antibody diluted at 1:2000 -
Western blot analysis of lysates from NIH/3T3 and RAW264.7 cells, using ATXN2L Antibody. The lane on the right is blocked with the synthesized peptide. -
Western blot analysis of the lysates from 293 cells using ATXN2L antibody.
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