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ELK Biotechnology
SKU:ES4616
IRAK-M Rabbit Polyclonal Antibody
IRAK-M Rabbit Polyclonal Antibody
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IRAK-M Rabbit Polyclonal Antibody
Overview
| Product name: | IRAK-M rabbit pAb |
| Alternative Names: | IRAK3; Interleukin-1 receptor-associated kinase 3; IRAK-3; IL-1 receptor-associated kinase M; IRAK-M |
| Applications: | WB;IHC;IF;ELISA |
| Recommended Dilutions: | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human IRAK3. AA range:491-540 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 68kD |
| GeneID(Human): | 11213 |
| Human Swiss-Prot No: | Q9Y616 |
| Cellular localization: | Cytoplasm . Nucleus . In dendritic cells, translocates into the nucleus upon IL33 stimulation. . |
| Background: | This gene encodes a member of the interleukin-1 receptor-associated kinase protein family. Members of this family are essential components of the Toll/IL-R immune signal transduction pathways. This protein is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling. Mutations in this gene are associated with a susceptibility to asthma. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2010], |
| Species Reactivity: | Human;Rat;Mouse; |
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Western Blot analysis of LOVO cells using IRAK-M Polyclonal Antibody -
Immunofluorescence analysis of HeLa cells, using IRAK3 Antibody. The picture on the right is blocked with the synthesized peptide. -
Immunohistochemistry analysis of paraffin-embedded human brain, using IRAK3 Antibody. The picture on the right is blocked with the synthesized peptide. -
Western blot analysis of lysates from K562 cells, using IRAK3 Antibody. The lane on the right is blocked with the synthesized peptide.
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