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ELK Biotechnology
SKU:ES4604
Cdc37 (phospho Ser13) Rabbit Polyclonal Antibody
Cdc37 (phospho Ser13) Rabbit Polyclonal Antibody
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Cdc37 (phospho Ser13) Rabbit Polyclonal Antibody
Overview
| Product name: | Cdc37 (phospho Ser13) rabbit pAb |
| Alternative Names: | CDC37; CDC37A; Hsp90 co-chaperone Cdc37; Hsp90 chaperone protein kinase-targeting subunit; p50Cdc37 |
| Applications: | WB;IHC;IF;ELISA |
| Recommended Dilutions: | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human CDC37 around the phosphorylation site of Ser13. AA range:1-50 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 44kD |
| GeneID(Human): | 11140 |
| Human Swiss-Prot No: | Q16543 |
| Cellular localization: | Cytoplasm . |
| Background: | The protein encoded by this gene is highly similar to Cdc 37, a cell division cycle control protein of Sacchromyces cerevisiae. This protein is a molecular chaperone with specific function in cell signal transduction. It has been shown to form complex with Hsp90 and a variety of protein kinases including CDK4, CDK6, SRC, RAF-1, MOK, as well as eIF2 alpha kinases. It is thought to play a critical role in directing Hsp90 to its target kinases. [provided by RefSeq, Jul 2008], |
| Species Reactivity: | Human;Mouse;Rat |
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Western Blot analysis of 3T3 cells using Phospho-Cdc37 (S13) Polyclonal Antibody -
Immunohistochemical analysis of paraffin-embedded Human lung cancer. Antibody was diluted at 1:100(4° overnight). High-pressure and temperature Tris-EDTA,pH8.0 was used for antigen retrieval. Negetive contrl (right) obtaned from antibody was pre-absorbe -
Immunohistochemistry analysis of paraffin-embedded human placenta, using CDC37 (Phospho-Ser13) Antibody. The picture on the right is blocked with the phospho peptide. -
Western blot analysis of lysates from HUVEC cells, using CDC37 (Phospho-Ser13) Antibody. The lane on the right is blocked with the phospho peptide.
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