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ELK Biotechnology
SKU:ES4562
PDE10A Rabbit Polyclonal Antibody
PDE10A Rabbit Polyclonal Antibody
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$248.00 USD
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PDE10A Rabbit Polyclonal Antibody
Overview
| Product name: | PDE10A rabbit pAb |
| Alternative Names: | PDE10A; cAMP and cAMP-inhibited cGMP 3'; 5'-cyclic phosphodiesterase 10A |
| Applications: | WB;ELISA;IHC |
| Recommended Dilutions: | WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000 |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human PDE10A. AA range:21-70 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 75kD |
| GeneID(Human): | 10846 |
| Human Swiss-Prot No: | Q9Y233 |
| Cellular localization: | Cytoplasm, cytosol . |
| Background: | The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase family. It plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This protein can hydrolyze both cAMP and cGMP to the corresponding nucleoside 5' monophosphate, but has higher affinity for cAMP, and is more efficient with cAMP as substrate. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Dec 2011], |
| Species Reactivity: | Human;Rat |
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Western Blot analysis of A549 cells using PDE10A Polyclonal Antibody -
Immunohistochemical analysis of paraffin-embedded human liver cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
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