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ELK Biotechnology

ES4537

DNA pol δ3 Rabbit Polyclonal Antibody

DNA pol δ3 Rabbit Polyclonal Antibody

$248.00 USD
$248.00 USD
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DNA pol δ3 Rabbit Polyclonal Antibody

Overview

Product name: DNA pol δ3 rabbit pAb
Alternative Names: POLD3; KIAA0039; DNA polymerase delta subunit 3; DNA polymerase delta subunit p66
Applications: WB;ELISA
Recommended Dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human POLD3. AA range:411-460
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 51kD
GeneID（Human）: 10714
Human Swiss-Prot No: Q15054
Cellular localization: Cytoplasm . Nucleus . Partially colocalizes with PCNA and POLD1 at S phase replication sites (PubMed:11595739). Recruited to DNA damage sites within 2 hours following UV irradiation (PubMed:20227374, PubMed:22801543). .
Background: This gene encodes the 66-kDa subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. The encoded protein plays a role in regulating the activity of DNA polymerase delta through interactions with other subunits and the processivity cofactor proliferating cell nuclear antigen (PCNA). Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Mar 2012],
Species Reactivity: Human;Mouse;Rat
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