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ELK Biotechnology

ES4507

SLU7 Rabbit Polyclonal Antibody

SLU7 Rabbit Polyclonal Antibody

$248.00 USD
$248.00 USD
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SLU7 Rabbit Polyclonal Antibody

Overview

Product name: SLU7 rabbit pAb
Alternative Names: SLU7; Pre-mRNA-splicing factor SLU7; hSlu7
Applications: WB;IHC
Recommended Dilutions: WB 1:500-2000;IHC-p 1:50-300
Immunogen: The antiserum was produced against synthesized peptide derived from human SLU7. AA range:113-162
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 65kD
GeneID（Human）: 10569
Human Swiss-Prot No: O95391
Cellular localization: Nucleus . Nucleus speckle . Cytoplasm . Predominantly nuclear. Shuttling between the nucleus and the cytoplasm is regulated by the CCHC-type zinc finger. Upon UV-C stress stimulus, the nuclear concentration of the protein decreases, affecting alternative splicing. Translocates from the nucleus to the cytoplasm after heat shock cell treatment. Accumulates in cytoplasmic vesicle-like organelles after heat shock treatment, which may represent stress granules. .
Background: Pre-mRNA splicing occurs in two sequential transesterification steps. The protein encoded by this gene is a splicing factor that has been found to be essential during the second catalytic step in the pre-mRNA splicing process. It associates with the spliceosome and contains a zinc knuckle motif that is found in other splicing factors and is involved in protein-nucleic acid and protein-protein interactions. [provided by RefSeq, Jul 2008],
Species Reactivity: Human;Mouse;Rat
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