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ELK Biotechnology
SKU:ES4478
MerTK/Tyro3 Rabbit Polyclonal Antibody
MerTK/Tyro3 Rabbit Polyclonal Antibody
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$248.00 USD
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MerTK/Tyro3 Rabbit Polyclonal Antibody
Overview
| Product name: | MerTK/Tyro3 rabbit pAb |
| Alternative Names: | MERTK; MER; Tyrosine-protein kinase Mer; Proto-oncogene c-Mer; Receptor tyrosine kinase MerTK; TYRO3; BYK; DTK; RSE; SKY; Tyrosine-protein kinase receptor TYRO3; Tyrosine-protein kinase DTK; Tyrosine-protein kinase RSE; Tyrosine-protein kin |
| Applications: | WB;IHC;IF;ELISA |
| Recommended Dilutions: | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human MER/SKY. AA range:716-765 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 97kD |
| GeneID(Human): | 10461/7301 |
| Human Swiss-Prot No: | Q12866/Q06418 |
| Cellular localization: | Cell membrane ; Single-pass type I membrane protein . |
| Background: | This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP). [provided by RefSeq, Jul 2008], |
| Species Reactivity: | Human;Mouse;Rat |
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Western Blot analysis of 3T3 cells using MerTK/Tyro3 Polyclonal Antibody -
Immunohistochemistry analysis of paraffin-embedded human brain tissue, using MER/SKY Antibody. The picture on the right is blocked with the synthesized peptide. -
Western blot analysis of lysates from NIH/3T3 cells, treated with EGF 200ng/ml 5', using MER/SKY Antibody. The lane on the right is blocked with the synthesized peptide.
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