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ELK Biotechnology

ES4475

Vav3 (phospho Tyr173) Rabbit Polyclonal Antibody

Vav3 (phospho Tyr173) Rabbit Polyclonal Antibody

$248.00 USD
$248.00 USD
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Vav3 (phospho Tyr173) Rabbit Polyclonal Antibody

Overview

Product name: Vav3 (phospho Tyr173) rabbit pAb
Alternative Names: VAV3; Guanine nucleotide exchange factor VAV3; VAV-3
Applications: WB;IHC;IF;ELISA
Recommended Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Immunogen: Synthesized phospho-peptide around the phosphorylation site of human Vav3 (phospho Tyr173)
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 100kD
GeneID（Human）: 10451
Human Swiss-Prot No: Q9UKW4
Cellular localization: intracellular,cytosol,plasma membrane,extracellular exosome,
Background: This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. This gene product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent, RAC1, and it associates maximally with the nucleotide-free states of these GTPases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008],
Species Reactivity: Human;Mouse
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