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ELK Biotechnology
SKU:ES4471
Cdc42EP2 Rabbit Polyclonal Antibody
Cdc42EP2 Rabbit Polyclonal Antibody
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$248.00 USD
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Cdc42EP2 Rabbit Polyclonal Antibody
Overview
| Product name: | Cdc42EP2 rabbit pAb |
| Alternative Names: | CDC42EP2; BORG1; CEP2; Cdc42 effector protein 2; Binder of Rho GTPases 1 |
| Applications: | WB;IHC;IF;ELISA |
| Recommended Dilutions: | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human BORG1. AA range:10-59 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 28kD |
| GeneID(Human): | 10435 |
| Human Swiss-Prot No: | O14613 |
| Cellular localization: | Endomembrane system ; Peripheral membrane protein . Cytoplasm, cytoskeleton . |
| Background: | CDC42, a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. The protein encoded by this gene is a member of the Borg family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to, and negatively regulate the function of CDC42. Coexpression of this protein with CDC42 suggested a role of this protein in actin filament assembly and cell shape control. [provided by RefSeq, Aug 2011], |
| Species Reactivity: | Human;Mouse;Rat |
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Western Blot analysis of K562 cells using Cdc42EP2 Polyclonal Antibody -
Western blot analysis of lysates from K562 cells, using BORG1 Antibody. The lane on the right is blocked with the synthesized peptide. -
Immunohistochemical analysis of paraffin-embedded human Squamous cell carcinoma of lung. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
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