p57 (phospho Thr310) Rabbit Polyclonal Antibody

Name: p57 (phospho Thr310) Rabbit Polyclonal Antibody
Brand: ELK Biotechnology
SKU: ES4453
Price: 248.0 USD
Availability: InStock

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p57 (phospho Thr310) Rabbit Polyclonal Antibody

Product name:	p57 (phospho Thr310) rabbit pAb
Alternative Names:	CDKN1C; KIP2; Cyclin-dependent kinase inhibitor 1C; Cyclin-dependent kinase inhibitor p57; p57Kip2
Applications:	WB;IHC;IF;ELISA
Recommended Dilutions:	Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Immunogen:	The antiserum was produced against synthesized peptide derived from human p57 Kip2 around the phosphorylation site of Thr310. AA range:267-316
Storage:	-20°C/1 year
Storage:	Rabbit
Clonality:	Polyclonal
Isotype:	IgG
Concentration:	1 mg/ml
Observed Band:	32kD
GeneID（Human）:	1028
Human Swiss-Prot No:	P49918
Cellular localization:	Nucleus .
Background:	This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2010],
Species Reactivity:	Human;Mouse

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