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ELK Biotechnology

SKU:ES4433

DEF-3 Rabbit Polyclonal Antibody

DEF-3 Rabbit Polyclonal Antibody

Regular price $248.00 USD
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DEF-3 Rabbit Polyclonal Antibody

Overview

Product name: DEF-3 rabbit pAb
Alternative Names: RBM6; DEF3; RNA-binding protein 6; Lung cancer antigen NY-LU-12; Protein G16; RNA-binding motif protein 6; RNA-binding protein DEF-3
Applications: WB;IHC;IF;ELISA
Recommended Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human RBM6. AA range:991-1040
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 150kD
GeneID(Human): 10180
Human Swiss-Prot No: P78332
Cellular localization: Nucleus .
Background: disease:Defects in RBM6 are found in non-small cell lung cancer (NSCLC) cell lines.,function:Specifically binds poly(G) RNA homopolymers in vitro.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 G-patch domain.,similarity:Contains 1 RRM (RNA recognition motif) domain.,tissue specificity:Ubiquitous in adults.,
Species Reactivity: Human;Mouse
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