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ELK Biotechnology
SKU:ES4430
LI-cadherin Rabbit Polyclonal Antibody
LI-cadherin Rabbit Polyclonal Antibody
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LI-cadherin Rabbit Polyclonal Antibody
Overview
| Product name: | LI-cadherin rabbit pAb |
| Alternative Names: | CDH17; Cadherin-17; Intestinal peptide-associated transporter HPT-1; Liver-intestine cadherin; LI-cadherin |
| Applications: | WB;IHC;IF;ELISA |
| Recommended Dilutions: | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human CDH17. AA range:341-390 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 99kD |
| GeneID(Human): | 1015 |
| Human Swiss-Prot No: | Q12864 |
| Cellular localization: | Cell membrane ; Single-pass type I membrane protein . |
| Background: | This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. The encoded protein is cadherin-like, consisting of an extracellular region, containing 7 cadherin domains, and a transmembrane region but lacking the conserved cytoplasmic domain. The protein is a component of the gastrointestinal tract and pancreatic ducts, acting as an intestinal proton-dependent peptide transporter in the first step in oral absorption of many medically important peptide-based drugs. The protein may also play a role in the morphological organization of liver and intestine. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2009], |
| Species Reactivity: | Human;Rat;Mouse; |
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Western Blot analysis of Jurkat cells using LI-cadherin Polyclonal Antibody -
Immunofluorescence analysis of HeLa cells, using CDH17 Antibody. The picture on the right is blocked with the synthesized peptide. -
Western blot analysis of lysates from Jurkat and HUVEC cells, using CDH17 Antibody. The lane on the right is blocked with the synthesized peptide. -
Immunohistochemical analysis of paraffin-embedded human tonsil. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
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