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ELK Biotechnology

SKU:ES4430

LI-cadherin Rabbit Polyclonal Antibody

LI-cadherin Rabbit Polyclonal Antibody

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LI-cadherin Rabbit Polyclonal Antibody

Overview

Product name: LI-cadherin rabbit pAb
Alternative Names: CDH17; Cadherin-17; Intestinal peptide-associated transporter HPT-1; Liver-intestine cadherin; LI-cadherin
Applications: WB;IHC;IF;ELISA
Recommended Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human CDH17. AA range:341-390
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 99kD
GeneID(Human): 1015
Human Swiss-Prot No: Q12864
Cellular localization: Cell membrane ; Single-pass type I membrane protein .
Background: This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. The encoded protein is cadherin-like, consisting of an extracellular region, containing 7 cadherin domains, and a transmembrane region but lacking the conserved cytoplasmic domain. The protein is a component of the gastrointestinal tract and pancreatic ducts, acting as an intestinal proton-dependent peptide transporter in the first step in oral absorption of many medically important peptide-based drugs. The protein may also play a role in the morphological organization of liver and intestine. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2009],
Species Reactivity: Human;Rat;Mouse;
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