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ELK Biotechnology

ES4378

GDF-6 Rabbit Polyclonal Antibody

GDF-6 Rabbit Polyclonal Antibody

$248.00 USD
$248.00 USD
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GDF-6 Rabbit Polyclonal Antibody

Overview

Product name: GDF-6 rabbit pAb
Alternative Names: GDF6; GDF16; Growth/differentiation factor 6; GDF-6; Growth/differentiation factor 16
Applications: WB;ELISA
Recommended Dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human GDF6. AA range:311-360
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 50kD
GeneID（Human）: 392255
Human Swiss-Prot No: Q6KF10
Cellular localization: Secreted .
Background: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein is required for normal formation of some bones and joints in the limbs, skull, and axial skeleton. Mutations in this gene are associated with Klippel-Feil syndrome, microphthalmia, and Leber congenital amaurosis. [provided by RefSeq, Sep 2016],
Species Reactivity: Human;Mouse;Rat
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