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ELK Biotechnology

SKU:ES4305

SOD-2 Rabbit Polyclonal Antibody

SOD-2 Rabbit Polyclonal Antibody

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SOD-2 Rabbit Polyclonal Antibody

Overview

Product name: SOD-2 rabbit pAb
Alternative Names: SOD2; Superoxide dismutase [Mn], mitochondrial
Applications: WB;IHC;IF;ELISA
Recommended Dilutions: IHC-p: 100-300.Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human SOD2. AA range:91-140
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 24kD
GeneID(Human): 6648
Human Swiss-Prot No: P04179
Cellular localization: Mitochondrion matrix.
Background: This gene is a member of the iron/manganese superoxide dismutase family. It encodes a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 1. [provided by RefSeq, Apr 2016],
Species Reactivity: Human;Mouse;Rat
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