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ELK Biotechnology
SKU:ES4291
AAT Rabbit Polyclonal Antibody
AAT Rabbit Polyclonal Antibody
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$248.00 USD
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AAT Rabbit Polyclonal Antibody
Overview
| Product name: | AAT rabbit pAb |
| Alternative Names: | SERPINA1; AAT; PI; Alpha-1-antitrypsin; Alpha-1 protease inhibitor; Alpha-1-antiproteinase; Serpin A1 |
| Applications: | WB;IHC;IF;ELISA |
| Recommended Dilutions: | Western Blot: 1/500 - 1/2000. IHC-p: 1:100-1:300. ELISA: 1/10000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the N-terminal region of human SERPINA1. AA range:1-50 |
| Storage: | -20°C/1 year |
| Storage: | Rabbit |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 47kD |
| GeneID(Human): | 5265 |
| Human Swiss-Prot No: | P01009 |
| Cellular localization: | Secreted. Endoplasmic reticulum. The S and Z allele are not secreted effectively and accumulate intracellularly in the endoplasmic reticulum.; [Short peptide from AAT]: Secreted, extracellular space, extracellular matrix. |
| Background: | The protein encoded by this gene is secreted and is a serine protease inhibitor whose targets include elastase, plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. Defects in this gene can cause emphysema or liver disease. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008], |
| Species Reactivity: | Human;Rat;Mouse; |
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Western Blot analysis of NIH-3T3 cells using AAT Polyclonal Antibody. Secondary antibody(catalog#:RS0002) was diluted at 1:20000 -
Immunohistochemical analysis of paraffin-embedded human-colon, antibody was diluted at 1:100 -
Immunohistochemical analysis of paraffin-embedded human-lung, antibody was diluted at 1:200
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