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ELK Biotechnology

ES4176

FOXP3 Rabbit Polyclonal Antibody

FOXP3 Rabbit Polyclonal Antibody

$248.00 USD
$248.00 USD
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FOXP3 Rabbit Polyclonal Antibody

Overview

Product name: FOXP3 rabbit pAb
Alternative Names: FOXP3; IPEX; JM2; Forkhead box protein P3; Scurfin
Applications: WB;IHC;IF;ELISA
Recommended Dilutions: Western Blot: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from the C-terminal region of human FOXP3. AA range:381-430
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 47kD
GeneID（Human）: 50943
Human Swiss-Prot No: Q9BZS1
Cellular localization: Nucleus . Cytoplasm . Predominantly expressed in the cytoplasm in activated conventional T-cells whereas predominantly expressed in the nucleus in regulatory T-cells (Treg). The 41 kDa form derived by proteolytic processing is found exclusively in the chromatin fraction of activated Treg cells (By similarity). .
Background: The protein encoded by this gene is a member of the forkhead/winged-helix family of transcriptional regulators. Defects in this gene are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX), also known as X-linked autoimmunity-immunodeficiency syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008],
Species Reactivity: Human;Mouse;Rat;Pig
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