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ELK Biotechnology
SKU:ES4169
ApoA-I Rabbit Polyclonal Antibody
ApoA-I Rabbit Polyclonal Antibody
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ApoA-I Rabbit Polyclonal Antibody
Overview
| Product name: | ApoA-I rabbit pAb |
| Alternative Names: | APOA1; Apolipoprotein A-I; Apo-AI; ApoA-I; Apolipoprotein A1 |
| Applications: | WB;IHC;IF;ELISA |
| Recommended Dilutions: | Western Blot: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the Internal region of human APOA1. AA range:81-130 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 31kD |
| GeneID(Human): | 335 |
| Human Swiss-Prot No: | P02647 |
| Cellular localization: | Secreted. |
| Background: | This gene encodes apolipoprotein A-I, which is the major protein component of high density lipoprotein (HDL) in plasma. The encoded preproprotein is proteolytically processed to generate the mature protein, which promotes cholesterol efflux from tissues to the liver for excretion, and is a cofactor for lecithin cholesterolacyltransferase (LCAT), an enzyme responsible for the formation of most plasma cholesteryl esters. This gene is closely linked with two other apolipoprotein genes on chromosome 11. Defects in this gene are associated with HDL deficiencies, including Tangier disease, and with systemic non-neuropathic amyloidosis. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein. [provided by RefSeq, Dec 2015], |
| Species Reactivity: | Human;Mouse |
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Western Blot analysis of K562 cells using ApoA-I Polyclonal Antibody. Secondary antibody(catalog#:RS0002) was diluted at 1:20000 -
Immunohistochemical analysis of paraffin-embedded human-liver, antibody was diluted at 1:100 -
Immunohistochemical analysis of paraffin-embedded human-liver, antibody was diluted at 1:100 -
Immunohistochemical analysis of paraffin-embedded human-lung, antibody was diluted at 1:100
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