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ELK Biotechnology

SKU:ES4166

CyPB Rabbit Polyclonal Antibody

CyPB Rabbit Polyclonal Antibody

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CyPB Rabbit Polyclonal Antibody

Overview

Product name: CyPB rabbit pAb
Alternative Names: PPIB; CYPB; Peptidyl-prolyl cis-trans isomerase B; PPIase B; CYP-S1; Cyclophilin B; Rotamase B; S-cyclophilin; SCYLP
Applications: WB;ELISA
Recommended Dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from the C-terminal region of human PPIB. AA range:151-200
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 24kD
GeneID(Human): 5479
Human Swiss-Prot No: P23284
Cellular localization: Virion . (Microbial infection).; Endoplasmic reticulum lumen . Melanosome . Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:17081065). .
Background: The protein encoded by this gene is a cyclosporine-binding protein and is mainly located within the endoplasmic reticulum. It is associated with the secretory pathway and released in biological fluids. This protein can bind to cells derived from T- and B-lymphocytes, and may regulate cyclosporine A-mediated immunosuppression. Variants have been identified in this protein that give rise to recessive forms of osteogenesis imperfecta. [provided by RefSeq, Oct 2009],
Species Reactivity: Human;Mouse;Rat
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