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ELK Biotechnology

ES4058

Cytokeratin 8 Rabbit Polyclonal Antibody

Cytokeratin 8 Rabbit Polyclonal Antibody

$248.00 USD
$248.00 USD
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Cytokeratin 8 Rabbit Polyclonal Antibody

Overview

Product name: Cytokeratin 8 rabbit pAb
Alternative Names: KRT8; CYK8; Keratin, type II cytoskeletal 8; Cytokeratin-8; CK-8; Keratin-8; K8; Type-II keratin Kb8
Applications: WB;IHC;IF;ELISA
Recommended Dilutions: Western Blot: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human K8 around the non-acetylation site of Lys483. AA range:434-483
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 53kD
GeneID（Human）: 3856
Human Swiss-Prot No: P05787
Cellular localization: Cytoplasm . Nucleus, nucleoplasm . Nucleus matrix .
Background: keratin 8(KRT8) Homo sapiens This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012],
Species Reactivity: Human;Rat;Mouse;
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