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ELK Biotechnology
SKU:ES4050
NUMB Rabbit Polyclonal Antibody
NUMB Rabbit Polyclonal Antibody
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$248.00 USD
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NUMB Rabbit Polyclonal Antibody
Overview
| Product name: | NUMB rabbit pAb |
| Alternative Names: | NUMB; Protein numb homolog; h-Numb; Protein S171 |
| Applications: | WB; IF;ELISA |
| Recommended Dilutions: | WB 1:500-2000; IF/ICC 1:100-500;ELISA 1:5000-20000 |
| Immunogen: | Synthesized peptide derived from the Internal region of human NUMB. |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 70kD |
| GeneID（Human）: | 8650 |
| Human Swiss-Prot No: | P49757 |
| Cellular localization: | Cell membrane ; Peripheral membrane protein ; Cytoplasmic side . Endosome membrane ; Peripheral membrane protein ; Cytoplasmic side . Localizes to perinuclear endosomes in an AAK1-dependent manner. . |
| Background: | The protein encoded by this gene plays a role in the determination of cell fates during development. The encoded protein, whose degradation is induced in a proteasome-dependent manner by MDM2, is a membrane-bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016], |
| Species Reactivity: | Human;Mouse;Rat |
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