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ELK Biotechnology

SKU:ES4047

GDI-2 Rabbit Polyclonal Antibody

GDI-2 Rabbit Polyclonal Antibody

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GDI-2 Rabbit Polyclonal Antibody

Overview

Product name: GDI-2 rabbit pAb
Alternative Names: GDI2; RABGDIB; Rab GDP dissociation inhibitor beta; Rab GDI beta; Guanosine diphosphate dissociation inhibitor 2; GDI-2
Applications: WB;IHC;IF;ELISA
Recommended Dilutions: Western Blot: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications.
Immunogen: Synthesized peptide derived from the C-terminal region of human GDI-2.
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 50kD
GeneID(Human): 2665
Human Swiss-Prot No: P50395
Cellular localization: Cytoplasm . Membrane ; Peripheral membrane protein .
Background: GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rabs. GDI2 is ubiquitously expressed. The GDI2 gene contains many repetitive elements indicating that it may be prone to inversion/deletion rearrangements. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008],
Species Reactivity: Human;Mouse;Rat
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