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ELK Biotechnology

ES4042

Pax-5 Rabbit Polyclonal Antibody

Pax-5 Rabbit Polyclonal Antibody

$248.00 USD
$248.00 USD
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Pax-5 Rabbit Polyclonal Antibody

Overview

Product name: Pax-5 rabbit pAb
Alternative Names: PAX5; Paired box protein Pax-5; B-cell-specific transcription factor; BSAP
Applications: WB;IHC;IF;ELISA
Recommended Dilutions: Western Blot: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human PAX5. AA range:171-220
Storage: -20°C/1 year
Storage: Rabbit
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 42kD
GeneID（Human）: 5079
Human Swiss-Prot No: Q02548
Cellular localization: Nucleus .
Background: This gene encodes a member of the paired box (PAX) family of transcription factors. The central feature of this gene family is a novel, highly conserved DNA-binding motif, known as the paired box. Paired box transcription factors are important regulators in early development, and alterations in the expression of their genes are thought to contribute to neoplastic transformation. This gene encodes the B-cell lineage specific activator protein that is expressed at early, but not late stages of B-cell differentiation. Its expression has also been detected in developing CNS and testis and so the encoded protein may also play a role in neural development and spermatogenesis. This gene is located at 9p13, which is involved in t(9;14)(p13;q32) translocations recurring in small lymphocytic lymphomas of the plasmacytoid subtype, and in derived large-cell lymphomas. This translocation brings the potent E-mu enhancer
Species Reactivity: Human;Mouse
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