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ELK Biotechnology
SKU:ES4022
MACC1 Rabbit Polyclonal Antibody
MACC1 Rabbit Polyclonal Antibody
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$248.00 USD
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MACC1 Rabbit Polyclonal Antibody
Overview
| Product name: | MACC1 rabbit pAb |
| Alternative Names: | MACC1; Metastasis-associated in colon cancer protein 1; SH3 domain-containing protein 7a5 |
| Applications: | WB;ELISA |
| Recommended Dilutions: | Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the Internal region of human MACC1. AA range:411-460 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 97kD |
| GeneID（Human）: | 346389 |
| Human Swiss-Prot No: | Q6ZN28 |
| Cellular localization: | Cytoplasm . Nucleus . Mainly found in the cytoplasm in non-metastasizing tumors. |
| Background: | MACC1 is a key regulator of the hepatocyte growth factor (HGF; MIM 142409)-HGF receptor (HGFR, or MET; MIM 164860) pathway, which is involved in cellular growth, epithelial-mesenchymal transition, angiogenesis, cell motility, invasiveness, and metastasis. Expression of MACC1 in colon cancer (MIM 114500) specimens is an independent prognostic indicator for metastasis formation and metastasis-free survival (Stein et al., 2009 [PubMed 19098908]).[supplied by OMIM, Mar 2009], |
| Species Reactivity: | Human;Mouse |
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