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ELK Biotechnology

ES3962

SPTLC1 Rabbit Polyclonal Antibody

SPTLC1 Rabbit Polyclonal Antibody

$248.00 USD
$248.00 USD
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SPTLC1 Rabbit Polyclonal Antibody

Overview

Product name: SPTLC1 rabbit pAb
Alternative Names: SPTLC1; LCB1; Serine palmitoyltransferase 1; Long chain base biosynthesis protein 1; LCB 1; Serine-palmitoyl-CoA transferase 1; SPT 1; SPT1
Applications: WB;IHC;IF;ELISA
Recommended Dilutions: Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications.
Immunogen: Synthesized peptide derived from SPTLC1 . at AA range: 411-460
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 52kD
GeneID（Human）: 10558
Human Swiss-Prot No: O15269
Cellular localization: Endoplasmic reticulum membrane ; Single-pass membrane protein .
Background: This gene encodes a member of the class-II pyridoxal-phosphate-dependent aminotransferase family. The encoded protein is the long chain base subunit 1 of serine palmitoyltransferase. Serine palmitoyltransferase converts L-serine and palmitoyl-CoA to 3-oxosphinganine with pyridoxal 5'-phosphate and is the key enzyme in sphingolipid biosynthesis. Mutations in this gene were identified in patients with hereditary sensory neuropathy type 1. Alternatively spliced variants encoding different isoforms have been identified. Pseudogenes of this gene have been defined on chromosomes 1, 6, 10, and 13. [provided by RefSeq, Jul 2013],
Species Reactivity: Human;Mouse;Rat
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