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ELK Biotechnology

ES3877

ET-1 Rabbit Polyclonal Antibody

ET-1 Rabbit Polyclonal Antibody

$248.00 USD
$248.00 USD
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ET-1 Rabbit Polyclonal Antibody

Overview

Product name: ET-1 rabbit pAb
Alternative Names: EDN1; Endothelin-1; Preproendothelin-1; PPET1
Applications: WB;IHC;IF;ELISA
Recommended Dilutions: IHC-p: 100-300.Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human EDN1. AA range:131-180
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 25kD
GeneID（Human）: 1906
Human Swiss-Prot No: P05305
Cellular localization: Secreted.
Background: This gene encodes a preproprotein that is proteolytically processed to generate a secreted peptide that belongs to the endothelin/sarafotoxin family. This peptide is a potent vasoconstrictor and its cognate receptors are therapeutic targets in the treatment of pulmonary arterial hypertension. Aberrant expression of this gene may promote tumorigenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015],
Species Reactivity: Human;Rat;Mouse;
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