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ELK Biotechnology
SKU:ES3870
AFP Rabbit Polyclonal Antibody
AFP Rabbit Polyclonal Antibody
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$248.00 USD
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AFP Rabbit Polyclonal Antibody
Overview
| Product name: | AFP rabbit pAb |
| Alternative Names: | AFP; HPAFP; Alpha-fetoprotein; Alpha-1-fetoprotein; Alpha-fetoglobulin |
| Applications: | WB;IHC;IF;ELISA |
| Recommended Dilutions: | Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the Internal region of human AFP. AA range:371-420 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 70kD |
| GeneID(Human): | 174 |
| Human Swiss-Prot No: | P02771 |
| Cellular localization: | Secreted. |
| Background: | This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. [provided by RefSeq, Jul 2008], |
| Species Reactivity: | Human;Rat;Mouse; |
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Western Blot analysis of mouse liver, mouse serum cells using AFP Polyclonal Antibody. Secondary antibody(catalog#:RS0002) was diluted at 1:20000 -
Immunohistochemical analysis of paraffin-embedded rat-brain, antibody was diluted at 1:100 -
Immunohistochemical analysis of paraffin-embedded mouse-brain, antibody was diluted at 1:100 -
Immunohistochemical analysis of paraffin-embedded mouse-brain, antibody was diluted at 1:100
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