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ELK Biotechnology
SKU:ES3729
ZFYVE19 Rabbit Polyclonal Antibody
ZFYVE19 Rabbit Polyclonal Antibody
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$248.00 USD
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ZFYVE19 Rabbit Polyclonal Antibody
Overview
| Product name: | ZFYVE19 rabbit pAb |
| Alternative Names: | ZFYVE19; MPFYVE; Zinc finger FYVE domain-containing protein 19; MLL partner containing FYVE domain |
| Applications: | WB;IHC;IF;ELISA |
| Recommended Dilutions: | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human ZFYVE19. AA range:311-360 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 50kD |
| GeneID(Human): | 84936 |
| Human Swiss-Prot No: | Q96K21 |
| Cellular localization: | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cleavage furrow . Midbody, Midbody ring . Localizes mainly on centrosomes in interphase and early mitosis. Localizes at the cleavage furrow and midbody ring in late mitosis and cytokinesis. . |
| Background: | disease:A chromosomal aberration involving ZFYVE19 is associated with acute myeloblastic leukemia (AML). Translocation t(11;15)(q23;q14) with MLL/HRX.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 FYVE-type zinc finger.,tissue specificity:Detected in brain, heart, skeletal muscle, kidney and liver., |
| Species Reactivity: | Human;Rat;Mouse; |
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Western Blot analysis of various cells using ZFYVE19 Polyclonal Antibody. Secondary antibody(catalog#:RS0002) was diluted at 1:20000 -
Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue, using ZFYVE19 Antibody. The picture on the right is blocked with the synthesized peptide. -
Western blot analysis of lysates from HT-29 cells, using ZFYVE19 Antibody. The lane on the right is blocked with the synthesized peptide.
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