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ELK Biotechnology

ES3713

XRCC1 Rabbit Polyclonal Antibody

XRCC1 Rabbit Polyclonal Antibody

$248.00 USD
$248.00 USD
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XRCC1 Rabbit Polyclonal Antibody

Overview

Product name: XRCC1 rabbit pAb
Alternative Names: XRCC1; DNA repair protein XRCC1; X-ray repair cross-complementing protein 1
Applications: WB;IHC;IF;ELISA
Recommended Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human XRCC1. AA range:517-566
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 70kD
GeneID（Human）: 7515
Human Swiss-Prot No: P18887
Cellular localization: Nucleus . Moves from the nucleoli to the global nuclear chromatin upon DNA damage. .
Background: The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq, Jul 2008],
Species Reactivity: Human;Mouse;Rat
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