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ELK Biotechnology

SKU:ES3693

VEGF-B Rabbit Polyclonal Antibody

VEGF-B Rabbit Polyclonal Antibody

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VEGF-B Rabbit Polyclonal Antibody

Overview

Product name: VEGF-B rabbit pAb
Alternative Names: VEGFB; VRF; Vascular endothelial growth factor B; VEGF-B; VEGF-related factor; VRF
Applications: WB;IHC;IF;ELISA
Recommended Dilutions: Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. IF 1:100-300 Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human VEGFB. AA range:91-140
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 21kD
GeneID(Human): 7423
Human Swiss-Prot No: P49765
Cellular localization: Secreted. Secreted but remains associated to cells or to the extracellular matrix unless released by heparin.
Background: This gene encodes a member of the PDGF (platelet-derived growth factor)/VEGF (vascular endothelial growth factor) family. The VEGF family members regulate the formation of blood vessels and are involved in endothelial cell physiology. This member is a ligand for VEGFR-1 (vascular endothelial growth factor receptor 1) and NRP-1 (neuropilin-1). Studies in mice showed that this gene was co-expressed with nuclear-encoded mitochondrial genes and the encoded protein specifically controlled endothelial uptake of fatty acids. Alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Sep 2011],
Species Reactivity: Human;Mouse;Rat
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