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ELK Biotechnology

ES3673

UDG Rabbit Polyclonal Antibody

UDG Rabbit Polyclonal Antibody

$248.00 USD
$248.00 USD
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UDG Rabbit Polyclonal Antibody

Overview

Product name: UDG rabbit pAb
Alternative Names: UNG; DGU; UNG1; UNG15; Uracil-DNA glycosylase; UDG
Applications: WB;IHC;IF;ELISA
Recommended Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human UNG. AA range:191-240
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 35kD
GeneID（Human）: 7374
Human Swiss-Prot No: P13051
Cellular localization: [Isoform 1]: Mitochondrion.; [Isoform 2]: Nucleus.
Background: This gene encodes one of several uracil-DNA glycosylases. One important function of uracil-DNA glycosylases is to prevent mutagenesis by eliminating uracil from DNA molecules by cleaving the N-glycosylic bond and initiating the base-excision repair (BER) pathway. Uracil bases occur from cytosine deamination or misincorporation of dUMP residues. Alternative promoter usage and splicing of this gene leads to two different isoforms: the mitochondrial UNG1 and the nuclear UNG2. The UNG2 term was used as a previous symbol for the CCNO gene (GeneID 10309), which has been confused with this gene, in the literature and some databases. [provided by RefSeq, Nov 2010],
Species Reactivity: Human;Mouse;Rat
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