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ELK Biotechnology
SKU:ES3670
UBR5 Rabbit Polyclonal Antibody
UBR5 Rabbit Polyclonal Antibody
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$248.00 USD
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UBR5 Rabbit Polyclonal Antibody
Overview
| Product name: | UBR5 rabbit pAb |
| Alternative Names: | UBR5; EDD; EDD1; HYD; KIAA0896; E3 ubiquitin-protein ligase UBR5; E3 ubiquitin-protein ligase; HECT domain-containing 1; Hyperplastic discs protein homolog; hHYD; Progestin-induced protein |
| Applications: | WB;IHC;IF;ELISA |
| Recommended Dilutions: | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human EDD. AA range:1-50 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 309kD |
| GeneID(Human): | 51366 |
| Human Swiss-Prot No: | O95071 |
| Cellular localization: | Nucleus. |
| Background: | This gene encodes a progestin-induced protein, which belongs to the HECT (homology to E6-AP carboxyl terminus) family. The HECT family proteins function as E3 ubiquitin-protein ligases, targeting specific proteins for ubiquitin-mediated proteolysis. This gene is localized to chromosome 8q22 which is disrupted in a variety of cancers. This gene potentially has a role in regulation of cell proliferation or differentiation. [provided by RefSeq, Jul 2008], |
| Species Reactivity: | Human;Mouse |
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Western Blot analysis of various cells using UBR5 Polyclonal Antibody. Secondary antibody(catalog#:RS0002) was diluted at 1:20000 cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA). -
Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using EDD Antibody. The picture on the right is blocked with the synthesized peptide. -
Western blot analysis of lysates from A549 cells, using EDD Antibody. The lane on the right is blocked with the synthesized peptide. -
Western blot analysis of the lysates from K562 cells using EDD antibody.
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