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ELK Biotechnology

ES3669

Ubr1 Rabbit Polyclonal Antibody

Ubr1 Rabbit Polyclonal Antibody

$248.00 USD
$248.00 USD
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Ubr1 Rabbit Polyclonal Antibody

Overview

Product name: Ubr1 rabbit pAb
Alternative Names: UBR1; E3 ubiquitin-protein ligase UBR1; N-recognin-1; Ubiquitin-protein ligase E3-alpha-1; Ubiquitin-protein ligase E3-alpha-I
Applications: WB;IHC;IF;ELISA
Recommended Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human UBR1. AA range:821-870
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 200kD
GeneID（Human）: 197131
Human Swiss-Prot No: Q8IWV7
Cellular localization: Cytoplasm, cytosol .
Background: The N-end rule pathway is one proteolytic pathway of the ubiquitin system. The recognition component of this pathway, encoded by this gene, binds to a destabilizing N-terminal residue of a substrate protein and participates in the formation of a substrate-linked multiubiquitin chain. This leads to the eventual degradation of the substrate protein. The protein described in this record has a RING-type zinc finger and a UBR-type zinc finger. Mutations in this gene have been associated with Johanson-Blizzard syndrome. [provided by RefSeq, Jul 2008],
Species Reactivity: Human;Mouse
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