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ELK Biotechnology

SKU:ES3653

Tuberin Rabbit Polyclonal Antibody

Tuberin Rabbit Polyclonal Antibody

Regular price $248.00 USD
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Tuberin Rabbit Polyclonal Antibody

Overview

Product name: Tuberin rabbit pAb
Alternative Names: TSC2; TSC4; Tuberin; Tuberous sclerosis 2 protein
Applications: WB;IHC;IF;ELISA
Recommended Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human Tuberin/TSC2. AA range:905-954
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 200kD
GeneID(Human): 7249
Human Swiss-Prot No: P49815
Cellular localization: Cytoplasm. Membrane; Peripheral membrane protein. At steady state found in association with membranes.
Background: Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],
Species Reactivity: Human;Mouse;Rat
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