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ELK Biotechnology

ES3638

Translin Rabbit Polyclonal Antibody

Translin Rabbit Polyclonal Antibody

$248.00 USD
$248.00 USD
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Translin Rabbit Polyclonal Antibody

Overview

Product name: Translin rabbit pAb
Alternative Names: TSN; Translin; Component 3 of promoter of RISC; C3PO
Applications: WB;IHC;IF;ELISA
Recommended Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human TSN. AA range:101-150
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 26kD
GeneID（Human）: 7247
Human Swiss-Prot No: Q15631
Cellular localization: Cytoplasm . Nucleus .
Background: This gene encodes a DNA-binding protein which specifically recognizes conserved target sequences at the breakpoint junction of chromosomal translocations. Translin polypeptides form a multimeric structure that is responsible for its DNA-binding activity. Recombination-associated motifs and translin-binding sites are present at recombination hotspots and may serve as indicators of breakpoints in genes which are fused by translocations. These binding activities may play a crucial role in chromosomal translocation in lymphoid neoplasms. This protein encoded by this gene, when complexed with translin-associated protein X, also forms a Mg ion-dependent endoribonuclease that promotes RNA-induced silencing complex (RISC) activation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2012],
Species Reactivity: Human;Mouse;Rat
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