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ELK Biotechnology

SKU:ES3616

TLK1 Rabbit Polyclonal Antibody

TLK1 Rabbit Polyclonal Antibody

Regular price $248.00 USD
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TLK1 Rabbit Polyclonal Antibody

Overview

Product name: TLK1 rabbit pAb
Alternative Names: TLK1; KIAA0137; Serine/threonine-protein kinase tousled-like 1; PKU-beta; Tousled-like kinase 1
Applications: WB;ELISA;IHC
Recommended Dilutions: WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
Immunogen: The antiserum was produced against synthesized peptide derived from human TLK1. AA range:201-250
Storage: -20°C/1 year
Storage: Rabbit
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 87kD
GeneID(Human): 9874
Human Swiss-Prot No: Q9UKI8
Cellular localization: Nucleus .
Background: Serine/threonine-protein kinase tousled-like 1 encoded by TLK1 is a serine/threonine kinase that may be involved in the regulation of chromatin assembly. The encoded protein is only active when it is phosphorylated, and this phosphorylation is cell cycle-dependent, with the maximal activity of this protein coming during S phase. The catalytic activity of this protein is diminished by DNA damage and by blockage of DNA replication. Three transcript variants encoding different isoforms have been found for this gene.
Species Reactivity: Human;Rat;Mouse;
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