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ELK Biotechnology
SKU:ES3580
TEL Rabbit Polyclonal Antibody
TEL Rabbit Polyclonal Antibody
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$248.00 USD
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TEL Rabbit Polyclonal Antibody
Overview
| Product name: | TEL rabbit pAb |
| Alternative Names: | ETV6; TEL; TEL1; Transcription factor ETV6; ETS translocation variant 6; ETS-related protein Tel1; Tel |
| Applications: | WB;IHC;IF;ELISA |
| Recommended Dilutions: | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human ETV6. AA range:371-420 |
| Storage: | -20°C/1 year |
| Storage: | Rabbit |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 53kD |
| GeneID(Human): | 2120 |
| Human Swiss-Prot No: | P41212 |
| Cellular localization: | Nucleus. |
| Background: | This gene encodes an ETS family transcription factor. The product of this gene contains two functional domains: a N-terminal pointed (PNT) domain that is involved in protein-protein interactions with itself and other proteins, and a C-terminal DNA-binding domain. Gene knockout studies in mice suggest that it is required for hematopoiesis and maintenance of the developing vascular network. This gene is known to be involved in a large number of chromosomal rearrangements associated with leukemia and congenital fibrosarcoma. [provided by RefSeq, Sep 2008], |
| Species Reactivity: | Human;Mouse;Rat |
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Western Blot analysis of various cells using TEL Polyclonal Antibody -
Immunofluorescence analysis of HeLa cells, using ETV6 Antibody. The picture on the right is blocked with the synthesized peptide. -
Western blot analysis of lysates from HeLa, HepG2, and Jurkat cells, using ETV6 Antibody. The lane on the right is blocked with the synthesized peptide. -
Immunohistochemical analysis of paraffin-embedded human Colon cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
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