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ELK Biotechnology

ES3565

TBX1 Rabbit Polyclonal Antibody

TBX1 Rabbit Polyclonal Antibody

$248.00 USD
$248.00 USD
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TBX1 Rabbit Polyclonal Antibody

Overview

Product name: TBX1 rabbit pAb
Alternative Names: TBX1; T-box transcription factor TBX1; T-box protein 1; Testis-specific T-box protein
Applications: WB;IHC;IF;ELISA
Recommended Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human TBX1. AA range:311-360
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 43kD
GeneID（Human）: 6899
Human Swiss-Prot No: O43435
Cellular localization: Nucleus .
Background: This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene product shares 98% amino acid sequence identity with the mouse ortholog. DiGeorge syndrome (DGS)/velocardiofacial syndrome (VCFS), a common congenital disorder characterized by neural-crest-related developmental defects, has been associated with deletions of chromosome 22q11.2, where this gene has been mapped. Studies using mouse models of DiGeorge syndrome suggest a major role for this gene in the molecular etiology of DGS/VCFS. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008],
Species Reactivity: Human;Rat;Mouse;
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