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ELK Biotechnology
SKU:ES3544
SYT Rabbit Polyclonal Antibody
SYT Rabbit Polyclonal Antibody
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$248.00 USD
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SYT Rabbit Polyclonal Antibody
Overview
| Product name: | SYT rabbit pAb |
| Alternative Names: | SS18; SSXT; SYT; Protein SSXT; Protein SYT; Synovial sarcoma translocated to X chromosome protein |
| Applications: | WB;IHC;IF;ELISA |
| Recommended Dilutions: | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human SSXT. AA range:1-50 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 45kD |
| GeneID(Human): | 6760 |
| Human Swiss-Prot No: | Q15532 |
| Cellular localization: | Nucleus . |
| Background: | disease:A chromosomal aberration involving SS18 may be a cause of synovial sarcoma. Translocation t(X;18)(p11.2;q11.2). The translocation is specifically found in more than 80% of synovial sarcoma. The fusion products SSXT-SSX1 or SSXT-SSX2 are probably responsible for transforming activity. Heterogeneity in the position of the breakpoint can occur (low frequency).,similarity:Belongs to the SS18 family.,tissue specificity:Fairly ubiquitously expressed. Expressed in synovial sarcomas and in other human cell lines. The fusion genes SSXT-SSX1 and SSXT-SSX2 are expressed only in synovial sarcomas., |
| Species Reactivity: | Human;Mouse;Rat |
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Western Blot analysis of various cells using SYT Polyclonal Antibody -
Western Blot analysis of COLO205 cells using SYT Polyclonal Antibody -
Western blot analysis of lysates from HepG2, Jurkat, and COLO205 cells, using SSXT Antibody. The lane on the right is blocked with the synthesized peptide. -
Immunohistochemical analysis of paraffin-embedded human tonsil. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
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