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ELK Biotechnology

SKU:ES3544

SYT Rabbit Polyclonal Antibody

SYT Rabbit Polyclonal Antibody

Regular price $248.00 USD
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SYT Rabbit Polyclonal Antibody

Overview

Product name: SYT rabbit pAb
Alternative Names: SS18; SSXT; SYT; Protein SSXT; Protein SYT; Synovial sarcoma translocated to X chromosome protein
Applications: WB;IHC;IF;ELISA
Recommended Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human SSXT. AA range:1-50
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 45kD
GeneID(Human): 6760
Human Swiss-Prot No: Q15532
Cellular localization: Nucleus .
Background: disease:A chromosomal aberration involving SS18 may be a cause of synovial sarcoma. Translocation t(X;18)(p11.2;q11.2). The translocation is specifically found in more than 80% of synovial sarcoma. The fusion products SSXT-SSX1 or SSXT-SSX2 are probably responsible for transforming activity. Heterogeneity in the position of the breakpoint can occur (low frequency).,similarity:Belongs to the SS18 family.,tissue specificity:Fairly ubiquitously expressed. Expressed in synovial sarcomas and in other human cell lines. The fusion genes SSXT-SSX1 and SSXT-SSX2 are expressed only in synovial sarcomas.,
Species Reactivity: Human;Mouse;Rat
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